The Microfluidics for Circulating Biomarkers 2019 Summit will be held on beautiful Coronado Island at the Marriott Resort & Spa in California (across the bay from downtown San Diego) on October 10th.  This conference is the companion summit to the SelectBIO Eleventh Annual Lab-on-a-Chip and Microfluidics World Congress 2019 which takes place October 7th – 9th, 2019. The conference aims to bring together researchers and industry participants from both academia and industry. The congress will focus on the latest innovations and developments in the Lab-on-a-Chip (LOAC) and Microfluidics fields. This summit brings together researchers for an intensive two-day highly-interactive set of sessions focusing on this emerging space.  The emphasis at this summit is the deployment and utilization of microfluidics technologies and approaches for the interrogation of circulating biomarkers such as Circulating Tumor Cells (CTCs), Extracellular Vesicles/Exosomes (EVs) and Circulating Cell-Free DNA (cfDNA) — the summit is a deep dive into the various technologies and applications in this space. In addition to presentations, there will be round-table discussions focusing on the current state-of-the-field and commercialization.

Redbud Labs will sponsor exhibits while at the conference. However, on Thursday, October 10th at 12 noon, Redbud’s CEO, Richard Spero, will be the Keynote speaker. Cartridge-Ready Isolation and Concentration of Extracellular Vesicles will be the title of Dr. Spero’s lecture and the talk abstract follows.

Despite decades of innovation, there is no accepted standard for isolation of circulating biomarkers in microfluidic systems. This creates a problem for developers of new biomarker assays and liquid biopsy tests. Traditional sample prep methods such as ultracentrifugation, affinity sorting with magnetic beads, or micro-filtration are acceptable for use in a discovery environment. However, these methods do not translate effectively to microfluidic cartridges, so promising assays must be completely re-implemented when moving from the bench to an integrated system. We present our work on a high-performance sample prep method for circulating biomarkers that translates easily from the bench to a microfluidic cartridge.